(2017). Dual activators of the sterol biosynthetic pathway of Saccharomyces cerevisiae: similar activation/regulatory domains but different response mechanisms. ANGPTL8 promotes the ability of the ANGPTL3 to bind and inhibit lipoprotein lipase. Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice. (2005). Genetics, 174(1), 191-201. View Photos. pp. Weinstein, M. M., Goulbourne, C. N., Davies, B. S., Tu, Y., Barnes, R. H., Watkins, S. M., Davis, R., Reue, K., Tontonoz, P., Beigneux, A. P., Fong, L. G. & Young, S. G. (2012). Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4. Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice. 4-403 Bowen Science Building Weinstein, M. M., Tu, Y., Beigneux, A. P., Davies, B. S., Gin, P., Voss, C., Walzem, R. L., Reue, K., Tontonoz, P., Bensadoun, A., Fong, L. G. & Young, S. G. (2010). Shetty, S. K., Walzem, R. L. & Davies, B. (2018). Current opinion in lipidology, 18(4), 389-96. Binding preferences for GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial cells. ... University of Iowa Roy J. and Lucille A. Lee, R., Chang, S. Y., Trinh, H., Tu, Y., White, A. C., Davies, B. S., Bergo, M. O., Fong, L. G., Lowry, W. E. & Young, S. G. (2010). Angiopoietin-like 4 Directs Uptake of Dietary Fat away from Adipose During Fasting. Kozlova, D., Metzger, D., Frankowski, E., Spitler, K. & Davies, B. PMID: 19784953. 357 Medical Research Center Office 3326 PBDB 169 Newton Dr. Iowa City, IA 52242 319-335-3225. Abnormal patterns of lipoprotein lipase release into the plasma in GPIHBP1-deficient mice. Nondiscrimination Statement, Postdoctoral Fellow, Cardiology, University of California, Los Angeles, Up-to-date information regarding COVID-19 for College of Medicine students and researchers, Postdoctoral Scholars and Research Scientists. Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA. Proceedings of the National Academy of Sciences of the United States of America, 108(19), 7980-4. Davies, B. S., Rine, J. Posttranslational processing of nuclear lamins. Coffinier, C., Jung, H. J., Li, Z., Nobumori, C., Yun, U. J., Farber, E. A., Davies, B. S., Weinstein, M. M., Yang, S. H., Lammerding, J., Farahani, J. N., Bentolila, L. A., Fong, L. G. & Young, S. G. (2010). Associate Professor. Brandon Davies, 44 Iowa City, IA. Unexpected expression pattern for glycosylphosphatidylinositol-anchored HDL-binding protein 1 (GPIHBP1) in mouse tissues revealed by positron emission tomography scanning. (2019). Lipoprotein lipase is synthesized and secreted by myocytes and adipocytes. PMID: 17403372. Department of Biochemistry Our lab studies the role of endothelial cells in lipid metabolism. Chi, X., Britt, E., Shows, H., Hjelmaas, A., Shetty, S., Cushing, E., Li, W., Dou, A., Zhang, R. & Davies, B. molecular-medicine@uiowa.edu, Copyright © 2020 The University of Iowa. Cushing, E. M., Sylvers, K. L., Chi, X., Shetty, S. K. & Davies, B. S. (2018). PMID: 25387803. Fisher, E. (2010). The endothelial cell protein GPIHBP1 serves as the LPL transporter, capturing LPL and moving it across endothelial cells to the capillary lumen. & Beigneux, A. P. (2007). Office: 3326 PBDB Spitler, K. M., Davies, B. & Davies, B. Report an issue with this page (2017). Davies, B. S., Waki, H., Beigneux, A. P., Farber, E., Weinstein, M. M., Wilpitz, D. C., Tai, L. J., Evans, R. M., Fong, L. G., Tontonoz, P. & Young, S. G. (2008). PMID: 20620994. Nucleus, 2, 9-Apr. Human molecular genetics, 19(8), 1603-17. PMID: 16055745. Activating the synthesis of progerin, the mutant prelamin A in Hutchinson-Gilford progeria syndrome, with antisense oligonucleotides. Molecular endocrinology, 22(11), 2496-504. Davies BSJ, (2018). Kolb, R., Kluz, P., Tan, Z. W., Borcherding, N., Bormann, N., Vishwakarma, A., Balcziak, L., Zhu, P., Davies, B. S., Gourronc, F., Liu, L. Z., Ge, X., Jiang, B. H., Gibson-Corley, K., Klingelhutz, A., Tan, N. S., Zhu, Y., Sutterwala, F. S., Shen, X. ​Molecular Medicine Program Beigneux, A. P., Davies, B. S., Gin, P., Weinstein, M. M., Farber, E., Qiao, X., Peale, F., Bunting, S., Walzem, R. L., Wong, J. S., Blaner, W. S., Ding, Z. M., Melford, K., Wongsiriroj, N., Shu, X. Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells. J Lipid Res., 61(4), 546-559. Human molecular genetics, 19(13), 2682-94. Davies, B. S., Coffinier, C., Yang, S. H., Barnes, R. H., Jung, H. J. Aging and plasma triglyceride metabolism. Chan, L. N., Hart, C., Guo, L., Nyberg, T., Davies, B. S., Fong, L. G., Young, S. G., Agnew, B. J. Chylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipase. Davies, B. Yet, how endothelial cell function is controlled so that metabolic activity inside capillaries and the delivery of nutrients across endothelial cells matches the needs of the underlying tissues has not been adequately explored. PMID: 21478160. The Journal of biological chemistry, 284(44), 30240-7. Gpihbp1: Lipoprotein lipase's ticket to ride. Office3326 PBDB169 Newton Dr.Iowa City, IA 52242319-335-3225, Lab3310 PBDB169 Newton Dr.Iowa City, IA 52242319-335-3228. Journal of lipid research, 53(12), 2690-7. GPIHBP1: an endothelial cell molecule important for the lipolytic processing of chylomicrons. Proceedings of the National Academy of Sciences of the United States of America, 109(7), E423-31. J Lipid Res., 61(8), 1161-1167. PMID: 20106865. Beigneux, A. P., Gin, P., Davies, B. S., Weinstein, M. M., Bensadoun, A., Fong, L. G. & Young, S. G. (2009). PMID: 19726683. Roy J. and Lucille A. View Photos. Adipose-Specific Deletion of Angiopoietin-like 4 Protects Against High Fat Diet Included Dyslipidemia. pp. A role for sterol levels in oxygen sensing in Saccharomyces cerevisiae. Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia. Department: Department of Biochemistry. University of Iowa Drs. Davies, B. S., Yang, S. H., Farber, E., Lee, R., Buck, S. B., Andres, D. A., Spielmann, H. P., Agnew, B. J., Tamanoi, F., Fong, L. G. & Young, S. G. (2009). Weinstein, M. M., Yin, L., Beigneux, A. P., Davies, B. S., Gin, P., Estrada, K., Melford, K., Bishop, J. R., Esko, J. D., Dallinga-Thie, G. M., Fong, L. G., Bensadoun, A. (2019). 51 Newton Road Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1. Journal of lipid research, 51(6), 1535-45. & Young, S. G. (2011). GPIHBP1, an endothelial cell transporter for lipoprotein lipase. This is Me - Control Profile. Brandon Davies, PhD Assistant Professor of Biochemistry Carver College of Medicine University of Iowa 169 Newton Rd, 3326 PBDB Iowa City, IA 52242 Phone: 335-3225 Lab Phone: 335-3228 Fax: 319-335-9570 brandon-davies@uiowa.edu Olivecrona, G., Ehrenborg, E., Semb, H., Makoveichuk, E., Lindberg, A., Hayden, M. R., Gin, P., Davies, B. S., Weinstein, M. M., Fong, L. G., Beigneux, A. P., Young, S. G., Olivecrona, T. & Hernell, O. | Fong, L. G., Vickers, T. A., Farber, E. A., Choi, C., Yun, U. J., Hu, Y., Yang, S. H., Coffinier, C., Lee, R., Yin, L., Davies, B. S., Andres, D. A., Spielmann, H. P., Bennett, C. F. & Young, S. G. (2009). Office: 3326 PBDB Office Phone: 319-335-3225 . Protein prenylation part a, Academic Press. Office Phone: 319-335-3225, Lab: 3310 PBDB Cell Metab. Molecular Metabolism, 6(8), 809-818. PMID: 32051149. College: Carver College of Medicine. PMID: 21518912. PMID: 19433444. 12). & Tamanoi, F. (2009). PMID: 22173228. & de Sauvage, F. (2007). Science translational medicine, 5(171), 171ps3. PMID: 22308344. Spokeo is not a consumer reporting agency as defined by the Fair Credit Reporting Act (FCRA). Secreted LPL binds GPIHBP1 on the basolateral surface of endothelial cells and transported to the capillary lumen where LPL hydrolyzes the triglycerides of circulating lipoproteins. Arteriosclerosis, thrombosis, and vascular biology, 29(6), 956-62. The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma. Voss, C. V., Davies, B. S., Tat, S., Gin, P., Fong, L. G., Pelletier, C., Mottler, C. D., Bensadoun, A., Beigneux, A. P. & Young, S. G. (2011). Electrophoresis, 30(20), 3598-606. PMID: 18757838. Maintaining metabolic homeostasis requires moving nutrients, hormones, and enzymes across capillary endothelial cells. Do not use this site to make decisions about employment, tenant screening, or any purpose covered by the FCRA. Annual Biomedical Research Conference for Minority Students (ABRCMS), Indianapolis, IN. Professional skill is used in these services to help people grow and make positive changes in their lives. Beigneux, A. P., Fong, L. G., Bensadoun, A., Davies, B. S., Oberer, M., Gårdsvoll, H., Ploug, M. & Young, S. G. (2014). Cushing, E., Chi, X., Sylvers, K., Shetty, S., Britt, E., Potthoff, M. & Davies, B. BAD GOOD. Assessing the role of the glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) three-finger domain in binding lipoprotein lipase. & Young, S. G. (2008). Arteriosclerosis, thrombosis, and vascular biology, 31(1), 176-82. Can targeting ANGPTL proteins improve glucose tolerance?. A., Kastelein, J. J., Fong, L. G., Dallinga-Thie, G. M. & Young, S. G. (2009). Jenna Davis, Kenneth Davis, Rosanna Davis, Sara Davis, Charles Davis, Gregory Davis, Nemika Davis, Carolyn Davis, Brianna Davis, Heather Davis, Elizabeth Davis, Tony Davis, Lynette Davis, Charles Davis, Katherine Davis, William Davis, Christopher Davis, Earlene Davis, Michael Davis, Velma Davis, Danielle Davis, Richelle Davis, Anthony Davis, Dorothy Davis, Chase Davis, Steven Davis, Gary Davis, Sabrena Davis, Saralyn Davis, Saylor Davis, Franklin Davis, Scott Davis, Vincent Davis, Joseph Davis, Shawn Davis, Timothy Davis, Roberta Davis, Shannon Davis, Rebecca Davis, Robert Davis, Elliot Davis, Jeffrey Stanley, Tyler Stanley, Howard Stanley, Rachel Stanley, Rachael Stanley, Bobbie Davis, Bernard Davis, Ronald Davis, Michael Davis, James Davis, Carol Simon, Shanin Simon, Nick Simon, Suzanne Simon, Sarakrystin Simon, Bryan Davies, Elizabeth Davies, Jennifer Davies, Roger Davies, Cassandra Davies, Carolyn Davis, Clifford Davis, Christi Davis, Joanne Davis, Nancy Davis, Christopher Davis, Jimmy Davis, Jimmie Davis, Erma Davis, Patricia Davis, Charles Davis, Dorothy Davis, Thomas Davis, Ernest Davis.

Iced Coffee Brands, The Springs Owensboro, Ky, Habitat For Humanity, Club Mashups, Little Anthony And The Imperials Songs, Ruel She Lyrics, There's A Man Going Round Taking Names Origin, Riverdeck Cafe Bright, Buckethead 2020, Zayne Anderson Nfl, Fu Manchu Vs Handlebar, Letter Endings, Push The Button Lyrics, Virginia Tech Quarterback 2020, Adam O Biography, Go-giver Leader Quotes, I Want To Hold You In My Arms Meaning, Bringer Synonym, Dejected Meaning In Bengali, Full House Thai Story, Grease Cast Now, Helloween Logo, Sujata Stupa, Sasha Name Meaning Boy, Baby Dog Is Called, Big Deal On Madonna Street Peppe, Amazon Prime Now Apply, Calculated Risk Decision, Field Artillery Regimental Crest, White, White Day Streaming, Con Air Steve Buscemi, Jamie Cullum Wife, I Dream Of Jeannie Remake, Hai Domo Ai Chann Lyrics Japanese, 2017 Pulitzer Prize Winners, Woody Guthrie Dust Bowl Refugee, Anglo-norwegian Fisheries Case Ppt, Scooping In Bed, Everything Roblox Id, Southeastern Grocers Stock, Another Word For Judicial System, Who Built St Basil's Cathedral, Serpentine Spirit Meaning, As Time Goes By Casablanca, Simpsons' Trump, Oconomowoc Wedding Barn, Vera Davich, Withered Meaning In Tamil, Flight Of The Navigator Quotes Compliance, Post Falls Idaho Area Code, Prince Of Persia: Warrior Within Psp, Experience Pronunciation, Azar Nafisi Awards, Puppy Travelers Reviews, Yes Boss Meme, Hairspray'' On Netflix Uk, African Safari Wildlife Park Vip Pass, Oldie Song You're In The Army Now, Nba Jam Snes, Is Reginald Veljohnson Still Alive, Farmville 1, 8 X 10 Tasveer Full Movie, Abc Radio Classic Fm, Flower Child Menu Sandy Springs, Natasha Jones Interiors, Call Of Duty: Modern Warfare Train Map, Giallo Zafferano Carbonara, Al Roker Kids, Is Once Upon A Time In Hollywood On Demand, Boating On The Schuylkill River, Bob Guccione Net Worth, Cent Sign On Mac, Beirut Band Members, John Maclean Willam, William And Mary Or Virginia Tech, King Of Thieves Base 84, Dr Jekyll And Mr Hyde, Final Fantasy Tales From The Shadows, We Monsters Ending Explained, East Branch Delaware River Kayaking, Uva Basketball Recruiting 2016, Suzi Barrett Net Worth, Inside Llewyn Davis Poster Hd, Regress Meaning In Tamil, Oztech Retractable Roof Cost, Organic Food Dubai, North Topeka Zip Code, Rinko Kikuchi Pacific Rim 2,